Drug General Information
Drug ID
D0Y5QO
Former ID
DIB012490
Drug Name
GK-128
Indication Emesis [ICD9: 787; ICD10:R11] Terminated [545075]
Company
Taisho Pharmaceutical Co Ltd
Structure
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2D MOL

3D MOL

Canonical SMILES
c1(c(=O)c2c3c(ccc2sc1)cccc3)Cn1c(ncc1)C.Cl
CAS Number
CAS 139958-03-5
Target and Pathway
Target(s) 5-Hydroxytryptamine 3 receptor Target Info Modulator [534513]
References
Ref 545075Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800002051)
Ref 534513Effect of a novel 5-hydroxytryptamine3 (5-HT3) receptor antagonist, GK-128, on 5-HT3 receptors mediating contractions and relaxations in guinea-pig distal colon. Gen Pharmacol. 1997 Sep;29(3):353-9.

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