TTD | Drug: D0Y5NT

Drug General Information
Drug ID	D0Y5NT
Former ID	DIB002249
Drug Name	VT-224
Synonyms	Cc-chemokine binding protein (inflammation), Viron
Indication	Inflammatory disease [ICD9: 140-229, 147, 173, 573.3, 710-719; ICD10:C11, C44, K75.9, M00-M25]		Investigative	[543912]
Company	Viron Therapeutics Inc
Target and Pathway
Target(s)	CC chemokine receptor	Target Info	Modulator	[543912]
KEGG Pathway	Cytokine-cytokine receptor interaction
KEGG Pathway	Chemokine signaling pathway
Reactome	Beta defensins
	Binding and entry of HIV virion
	Chemokine receptors bind chemokines
	G alpha (i) signalling events
WikiPathways	GPCRs, Class A Rhodopsin-like
	Peptide GPCRs
	GPCR ligand binding
	GPCR downstream signaling
References
Ref 543912	(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 67).
Ref 543912	(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 67).

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Drug Information