TTD | Drug: D0XP5P

Drug General Information
Drug ID	D0XP5P
Former ID	DIB020262
Drug Name	LY063518
Synonyms	LY 063518; LY-063518
Drug Type	Small molecular drug
Indication	Discovery agent		Investigative	[539128]
Structure		Download 2D MOL 3D MOL
Formula	C12H11ClN4S
InChI	InChI=1S/C12H11ClN4S/c13-10-7-6-9(18-10)11(16-17-12(14)15)8-4-2-1-3-5-8/h1-7H,(H4,14,15,17)/b16-11-
InChIKey	LXZSGGMOFNDLPW-WJDWOHSUSA-N
PubChem Compound ID	23786507
PubChem Substance ID	47359959, 48179776
Target and Pathway
Target(s)	5-hydroxytryptamine 2A receptor	Target Info	Antagonist	[534232]
KEGG Pathway	Calcium signaling pathway
	Neuroactive ligand-receptor interaction
	Gap junction
	Serotonergic synapse
	Inflammatory mediator regulation of TRP channels
PANTHER Pathway	5HT2 type receptor mediated signaling pathway
Reactome	Serotonin receptors
Reactome	G alpha (q) signalling events
WikiPathways	Serotonin Receptor 2 and STAT3 Signaling
	Serotonin Receptor 2 and ELK-SRF/GATA4 signaling
	SIDS Susceptibility Pathways
	Monoamine GPCRs
	GPCRs, Class A Rhodopsin-like
	Gastrin-CREB signalling pathway via PKC and MAPK
	GPCR ligand binding
	GPCR downstream signaling
	GPCRs, Other
References
Ref 539128	(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 178).
Ref 534232	A novel class of 5-HT2A receptor antagonists: aryl aminoguanidines. Life Sci. 1996;59(15):1259-68.

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Drug Information