Drug Information
Drug General Information | |||||
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Drug ID |
D0X9PI
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Former ID |
DIB019565
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Drug Name |
compound 68
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Drug Type |
Small molecular drug
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Structure |
Download2D MOL |
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Formula |
C17H11BrFN5OS
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InChI |
InChI=1S/C17H11BrFN5OS/c1-25-15(20)17-24-12-5-4-11-13(14(12)26-17)16(22-7-21-11)23-10-3-2-8(18)6-9(10)19/h2-7,20H,1H3,(H,21,22,23)
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InChIKey |
ZBELDPMWYXDLNY-UHFFFAOYSA-N
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PubChem Compound ID | |||||
PubChem Substance ID | |||||
Target and Pathway | |||||
Target(s) | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | Target Info | Inhibitor | [532825] | |
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1B | Target Info | Inhibitor | [532825] | ||
References | |||||
Ref 527816 | Constitutive Dyrk1A is abnormally expressed in Alzheimer disease, Down syndrome, Pick disease, and related transgenic models. Neurobiol Dis. 2005 Nov;20(2):392-400. | ||||
Ref 532825 | Tricyclic Pyrimidines As Inhibitors of DYRK1A/DYRK1B As Potential Treatment for Down's Syndrome or Alzheimer's Disease. ACS Med Chem Lett. 2013 Apr 26;4(6):502-3. |
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