Drug General Information
Drug ID
D0X6PG
Former ID
DIB012332
Drug Name
LY-274614
Drug Type
Small molecular drug
Indication Dementia [ICD9: 290-294; ICD10:F01-F07] Terminated [544875]
Company
Eli Lilly & Co
Structure
Download
2D MOL

3D MOL

Formula
C11H20NO5P
Canonical SMILES
P(=O)(C[C@@H]1C[C@@H]2C[C@H](NC[C@@H]2CC1)C(=O)O)(O)O
CAS Number
CAS 136109-04-1
PubChem Compound ID
Target and Pathway
Target(s) NMDA receptor Target Info Modulator [533610]
References
Ref 544875Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800001393)
Ref 533610The NMDA receptor antagonists, LY274614 and MK-801, and the nitric oxide synthase inhibitor, NG-nitro-L-arginine, attenuate analgesic tolerance to the mu-opioid morphine but not to kappa opioids. Pain. 1994 Jan;56(1):69-75.

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