Drug General Information
Drug ID	D0X6LZ
Former ID	DIB018590
Drug Name	3-chlorotyrosine
Drug Type	Small molecular drug
Indication	Discovery agent		Investigative	[468178]
Structure		Download 2D MOL 3D MOL
Formula	C9H10ClNO3
InChI	InChI=1S/C9H10ClNO3/c10-6-3-5(1-2-8(6)12)4-7(11)9(13)14/h1-3,7,12H,4,11H2,(H,13,14)
InChIKey	ACWBBAGYTKWBCD-UHFFFAOYSA-N
PubChem Compound ID	119226
PubChem Substance ID	6008011, 10238398, 14818878, 29300158, 50065134, 57339388, 75612601, 83584729, 103129672, 104407834, 117461199, 125357060, 125536908, 125658372, 126524197, 131325289, 135074455, 136159797, 137323677, 138733030, 145470084, 162138098, 163059354, 165354563, 178101807, 206255106, 226521326, 250135365
Target and Pathway
Target(s)	Tyrosine 3-monooxygenase	Target Info	Inhibitor	[543389]
BioCyc Pathway	Catecholamine biosynthesis
KEGG Pathway	Tyrosine metabolism
	Metabolic pathways
	Dopaminergic synapse
	Prolactin signaling pathway
	Parkinson's disease
	Cocaine addiction
	Amphetamine addiction
	Alcoholism
PANTHER Pathway	Adrenaline and noradrenaline biosynthesis
	Parkinson disease
	Dopamine receptor mediated signaling pathway
	Nicotine pharmacodynamics pathway
Pathway Interaction Database	ATF-2 transcription factor network
	AP-1 transcription factor network
	p38 signaling mediated by MAPKAP kinases
	Alpha-synuclein signaling
PathWhiz Pathway	Catecholamine Biosynthesis
WikiPathways	Monoamine Transport
	SIDS Susceptibility Pathways
	Biogenic Amine Synthesis
	Dopaminergic Neurogenesis
	Metabolism of amino acids and derivatives
	Dopamine metabolism
	Parkinsons Disease Pathway
	Nicotine Activity on Dopaminergic Neurons
References
Ref 468178	(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 5114).
Ref 543389	(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 1243).

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