Drug General Information
Drug ID	D0X5AA
Former ID	DNC011518
Drug Name	AMIFLAMINE
Drug Type	Small molecular drug
Indication	Discovery agent		Investigative	[533479]
Structure		Download 2D MOL 3D MOL
Formula	C12H20N2
Canonical SMILES	CC1=C(C=CC(=C1)N(C)C)CC(C)N
InChI	1S/C12H20N2/c1-9-7-12(14(3)4)6-5-11(9)8-10(2)13/h5-7,10H,8,13H2,1-4H3
InChIKey	HFQMYSHATTXRTC-UHFFFAOYSA-N
CAS Number	CAS 77518-07-1
PubChem Compound ID	71221
Target and Pathway
Target(s)	Sodium-dependent noradrenaline transporter	Target Info	Inhibitor	[533479]
PANTHER Pathway	Adrenaline and noradrenaline biosynthesis
Reactome	Na+/Cl- dependent neurotransmitter transporters
WikiPathways	Monoamine Transport
	NRF2 pathway
	Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compounds
References
Ref 533479	J Med Chem. 1986 Aug;29(8):1406-12.Selective monoamine oxidase inhibitors. 3. Cyclic compounds related to 4-aminophenethylamine. Preparation and neuron-selective action of some 5-(2-aminoethyl)-2,3-dihydroindoles.
Ref 533479	J Med Chem. 1986 Aug;29(8):1406-12.Selective monoamine oxidase inhibitors. 3. Cyclic compounds related to 4-aminophenethylamine. Preparation and neuron-selective action of some 5-(2-aminoethyl)-2,3-dihydroindoles.

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