Drug Information
Drug General Information | |||||
---|---|---|---|---|---|
Drug ID |
D0X4ZL
|
||||
Former ID |
DIB003476
|
||||
Drug Name |
AN-1792
|
||||
Synonyms |
Betabloc; AIP-001
|
||||
Drug Type |
Small molecular drug
|
||||
Indication | Alzheimer disease [ICD9: 331; ICD10:G30] | Phase 2 | [521492] | ||
Company |
Elan Pharmaceutical Research
|
||||
Structure |
Download2D MOL |
||||
Formula |
C16H26ClNO
|
||||
Canonical SMILES |
CCC(C)[NH2+]CC(C1=CC2=C(CCCC2)C=C1)O.[Cl-]
|
||||
InChI |
1S/C16H25NO.ClH/c1-3-12(2)17-11-16(18)15-9-8-13-6-4-5-7-14(13)10-15;/h8-10,12,16-18H,3-7,11H2,1-2H3;1H
|
||||
InChIKey |
KHBXORBAOCQNMC-UHFFFAOYSA-N
|
||||
PubChem Compound ID | |||||
PubChem Substance ID | |||||
Target and Pathway | |||||
Target(s) | Amyloid beta A4 protein | Target Info | Inhibitor | [528396] | |
KEGG Pathway | Notch signaling pathway | ||||
Alzheimer's disease | |||||
Reactome | Nuclear signaling by ERBB4 | ||||
Degradation of the extracellular matrix | |||||
Regulated proteolysis of p75NTR | |||||
NRIF signals cell death from the nucleus | |||||
Activated NOTCH1 Transmits Signal to the Nucleus | |||||
Constitutive Signaling by NOTCH1 PEST Domain Mutants | |||||
Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants | |||||
EPH-ephrin mediated repulsion of cells | |||||
References |
If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.