Drug Information

Drug General Information
Drug ID
D0X3VM
Former ID
DIB021176
Drug Name
VU0155041
Synonyms
VU-0155041; VU 0155041
Drug Type
Small molecular drug
Indication Discovery agent Investigative [540283]
Structure
Download
2D MOL
Formula
C14H15Cl2NO3
InChI
InChI=1S/C14H15Cl2NO3/c15-8-5-9(16)7-10(6-8)17-13(18)11-3-1-2-4-12(11)14(19)20/h5-7,11-12H,1-4H2,(H,17,18)(H,19,20)/t11-,12+/m0/s1
InChIKey
VSMUYYFJVFSVCA-NWDGAFQWSA-N
PubChem Compound ID
888023
PubChem Substance ID
44490893, 58049881, 79891882, 84368034, 99000373, 103702085, 104155580, 110027523, 162248277, 163138668, 170019978, 172919855, 178100356, 202535710, 215767571, 226692630
Target and Pathway
Target(s) Metabotropic glutamate receptor 4 Target Info Modulator (allosteric modulator) [529617]
KEGG Pathway Neuroactive ligand-receptor interaction
Glutamatergic synapse
Taste transduction
PANTHER Pathway Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway
Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway
Metabotropic glutamate receptor group III pathway
Reactome G alpha (i) signalling events
Class C/3 (Metabotropic glutamate/pheromone receptors)
WikiPathways GPCRs, Class C Metabotropic glutamate, pheromone
GPCR ligand binding
GPCR downstream signaling
References
Ref 540283(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 3323).
Ref 529617Discovery, characterization, and antiparkinsonian effect of novel positive allosteric modulators of metabotropic glutamate receptor 4. Mol Pharmacol. 2008 Nov;74(5):1345-58.

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