Drug Information
Drug General Information | |||||
---|---|---|---|---|---|
Drug ID |
D0X0WU
|
||||
Former ID |
DIB011114
|
||||
Drug Name |
Tolperisone
|
||||
Synonyms |
Agileo; Viveo; AV-650; SPH-3047; Tolperisone (controlled-release); Tolperisone (controlled-release), Sanochemia; Tolperisone (controlled-release), Sanochemia/Avigen
|
||||
Drug Type |
Small molecular drug
|
||||
Indication | Muscle spasm [ICD10:M62.838] | Approved | [551871] | ||
Company |
Sanochemia Pharmazeutika AG
|
||||
Structure |
Download2D MOL |
||||
Formula |
C16H24ClNO
|
||||
Canonical SMILES |
C(=O)(C(CN1CCCCC1)C)c1ccc(cc1)C
|
||||
CAS Number |
CAS 728-88-1
|
||||
PubChem Compound ID | |||||
Target and Pathway | |||||
Target(s) | Voltage-gated sodium channel | Target Info | Modulator | [527704], [551871] | |
Voltage-dependent calcium channel | Target Info | Modulator | [527704], [530122] | ||
References | |||||
Ref 527704 | Tolperisone-type drugs inhibit spinal reflexes via blockade of voltage-gated sodium and calcium channels. J Pharmacol Exp Ther. 2005 Dec;315(3):1237-46. Epub 2005 Aug 26. | ||||
Ref 530122 | Inhibitory effect of glutamate release from rat cerebrocortical synaptosomes by dextromethorphan and its metabolite 3-hydroxymorphinan. Neurochem Int. 2009 Jul;54(8):526-34. | ||||
Ref 551871 | Drugs@FDA. U.S. Food and Drug Administration. U.S. Department of Health & Human Services. 2015 |
If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.