Drug Information
Drug General Information | |||||
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Drug ID |
D0WU9R
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Former ID |
DNC004182
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Drug Name |
L-741742
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Drug Type |
Small molecular drug
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Indication | Discovery agent | Investigative | [540264] | ||
Structure |
Download2D MOL |
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Formula |
C23H25ClN2O
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InChI |
InChI=1S/C23H25ClN2O/c1-17-22(25-27-23(17)20-7-9-21(24)10-8-20)19-12-15-26(16-13-19)14-11-18-5-3-2-4-6-18/h2-10,19H,11-16H2,1H3
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InChIKey |
QDMAKDIDFJTXEL-UHFFFAOYSA-N
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PubChem Compound ID | |||||
PubChem Substance ID | |||||
Target and Pathway | |||||
Target(s) | Sodium channel | Target Info | Inhibitor | [525540] | |
D(3) dopamine receptor | Target Info | Inhibitor | [534132] | ||
Voltage-gated sodium channel subunit alpha Nav1.3 | Target Info | Inhibitor | [525540] | ||
D(4) dopamine receptor | Target Info | Inhibitor | [534132] | ||
References | |||||
Ref 525540 | J Med Chem. 1999 Jul 15;42(14):2706-15.1-(3-Cyanobenzylpiperidin-4-yl)-5-methyl-4-phenyl-1, 3-dihydroimidazol-2-one: a selective high-affinity antagonist for the human dopamine D(4) receptor with excellent selectivity over ion channels. | ||||
Ref 534132 | J Med Chem. 1996 May 10;39(10):1943-5.5-(4-Chlorophenyl)-4-methyl-3-(1-(2-phenylethyl)piperidin-4-yl)isoxazole: a potent, selective antagonist at human cloned dopamine D4 receptors. |
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