Drug Information
Drug General Information | |||||
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Drug ID |
D0W9MM
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Former ID |
DAP000785
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Drug Name |
Vinblastine
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Synonyms |
Nincaluicolflastine; Rozevin; VLB; Vinblastin; Vinblastina; Vinblastinum; Vincaleucoblastin; Vincaleucoblastine; Vincaleukoblastine; Vincoblastine; Vinblastina [DCIT]; VR-8; Vinblastina (TN); Vinblastine (INN); Vinblastine [INN:BAN]; Vinblastinum [INN-Latin]; NDC 0002-1452-01; (2ALPHA,2'BETA,3BETA,4ALPHA,5BETA)-VINCALEUKOBLASTINE; (2xi,3beta,4'beta,19xi)-vincaleukoblastine; 1H-Indolizino(8,1-cd)carbazole-5-carboxylic acid
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Drug Type |
Small molecular drug
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Therapeutic Class |
Anticancer Agents
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Company |
Eli Lilly And Co
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Structure |
Download2D MOL |
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Formula |
C46H58N4O9
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InChI |
InChI=1S/C46H58N4O9/c1-8-42(54)23-28-24-45(40(52)57-6,36-30(15-19-49(25-28)26-42)29-13-10-11-14-33(29)47-36)32-21-31-34(22-35(32)56-5)48(4)38-44(31)17-20-50-18-12-16-43(9-2,37(44)50)39(59-27(3)51)46(38,55)41(53)58-7/h10-14,16,21-22,28,37-39,47,54-55H,8-9,15,17-20,23-26H2,1-7H3/t28-,37-,38+,39+,42-,43+,44+,45-,46-/m0/s1
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InChIKey |
JXLYSJRDGCGARV-CFWMRBGOSA-N
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CAS Number |
CAS 865-21-4
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PubChem Compound ID | |||||
PubChem Substance ID |
7891062, 8160040, 15945566, 16702846, 24262986, 25641143, 29281493, 46393695, 48034812, 49855966, 50104049, 50637221, 57328088, 85788295, 92718122, 93167219, 103229487, 103924566, 104331509, 124886802, 126628575, 126690312, 127342232, 127342233, 134338070, 134980402, 136126664, 136959342, 137001867, 141857134, 152104919, 162184753, 165280031, 175268513, 178103457, 179335179, 184812178, 223683512, 223832241, 226395766
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ChEBI ID |
ChEBI:27375
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SuperDrug ATC ID |
L01CA01
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SuperDrug CAS ID |
cas=000865214
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Drug Resistance Mutation (DRM) | |||||
DRM | DRM Info | ||||
Target and Pathway | |||||
Target(s) | Tubulin beta-2 chain | Target Info | Inhibitor | [535740] | |
References | |||||
Ref 541931 | (http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 6851). | ||||
Ref 551871 | Drugs@FDA. U.S. Food and Drug Administration. U.S. Department of Health & Human Services. 2015 |
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