| Drug General Information |
| Drug ID |
D0W4WF
|
| Former ID |
DNC006320
|
| Drug Name |
EFFUSOL
|
| Drug Type |
Small molecular drug
|
| Indication |
Discovery agent
|
Investigative |
[1]
|
|---|
| Structure |
|
Download
2D MOL
3D MOL
|
| Formula |
C17H16O2
|
| Canonical SMILES |
CC1=C(C=CC2=C1CCC3=C2C(=CC(=C3)O)C=C)O
|
| InChI |
1S/C17H16O2/c1-3-11-8-13(18)9-12-4-5-14-10(2)16(19)7-6-15(14)17(11)12/h3,6-9,18-19H,1,4-5H2,2H3
|
| InChIKey |
GEXAPRXWKRZPCK-UHFFFAOYSA-N
|
| PubChem Compound ID |
|
| Target and Pathway |
| Target(s) |
Estrogen receptor beta |
Target Info |
Inhibitor |
[1]
|
|---|
| Estrogen receptor |
Target Info |
Inhibitor |
[1]
|
|
KEGG Pathway
|
Estrogen signaling pathway
|
|
Prolactin signaling pathwayhsa04915:Estrogen signaling pathway
|
|
Prolactin signaling pathway
|
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Thyroid hormone signaling pathway
|
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Endocrine and other factor-regulated calcium reabsorption
|
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Proteoglycans in cancer
|
|
NetPath Pathway
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FSH Signaling Pathway
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EGFR1 Signaling Pathway
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RANKL Signaling Pathway
|
|
Pathway Interaction Database
|
Plasma membrane estrogen receptor signaling
|
|
Validated nuclear estrogen receptor beta network
|
|
Validated nuclear estrogen receptor alpha networksmad2_3nuclearpathway:Regulation of nuclear SMAD2/3 signaling
|
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Signaling events mediated by HDAC Class II
|
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LKB1 signaling events
|
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Regulation of Telomerase
|
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ATF-2 transcription factor network
|
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AP-1 transcription factor network
|
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FOXM1 transcription factor network
|
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Validated nuclear estrogen receptor alpha network
|
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Signaling mediated by p38-alpha and p38-beta
|
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FOXA1 transcription factor network
|
|
Reactome
|
Nuclear Receptor transcription pathwayR-HSA-1251985:Nuclear signaling by ERBB4
|
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Nuclear Receptor transcription pathway
|
|
WikiPathways
|
SIDS Susceptibility Pathways
|
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Ovarian Infertility Genes
|
|
Integrated Pancreatic Cancer Pathway
|
|
Nuclear ReceptorsWP712:Estrogen signaling pathway
|
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Nuclear Receptors Meta-Pathway
|
|
Estrogen Receptor Pathway
|
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Signaling by ERBB4
|
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JAK/STAT
|
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Leptin signaling pathway
|
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miR-targeted genes in muscle cell - TarBase
|
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Integrated Breast Cancer Pathway
|
|
Nuclear Receptors
|
| References |
| REF 1 | Bioorg Med Chem Lett. 2006 Mar 15;16(6):1468-72. Epub 2006 Jan 18.6H-Benzo[c]chromen-6-one derivatives as selective ERbeta agonists. |
|---|
