Drug Information

Drug General Information
Drug ID
D0W3XD
Former ID
DIB020464
Drug Name
N',2-diphenylquinoline-4-carbohydrazide
Synonyms
compound 2g [PMID: 16950620]
Drug Type
Small molecular drug
Indication Discovery agent Investigative [528420]
Structure
Download
2D MOL
Formula
C25H21N3O4
InChI
InChI=1S/C25H21N3O4/c1-31-23-21(24(29)27-28(25(30)32-2)18-13-7-4-8-14-18)19-15-9-10-16-20(19)26-22(23)17-11-5-3-6-12-17/h3-16H,1-2H3,(H,27,29)
InChIKey
JLSTVOPSMZBZSR-UHFFFAOYSA-N
PubChem Compound ID
16049828
PubChem Substance ID
24436214, 26594971, 29614488, 103507327, 104076856, 135650676, 225132632, 229929118, 248335098
Target and Pathway
Target(s) Nigral tachykinin NK(3) receptor Target Info Antagonist [528420]
KEGG Pathway Calcium signaling pathway
Neuroactive ligand-receptor interaction
Reactome G alpha (q) signalling events
WikiPathways Gastrin-CREB signalling pathway via PKC and MAPK
Peptide GPCRs
GPCR ligand binding
GPCR downstream signaling
References
Ref 528420Bioorg Med Chem Lett. 2006 Nov 15;16(22):5748-51. Epub 2006 Sep 6.N',2-diphenylquinoline-4-carbohydrazide based NK3 receptor antagonists.
Ref 528420Bioorg Med Chem Lett. 2006 Nov 15;16(22):5748-51. Epub 2006 Sep 6.N',2-diphenylquinoline-4-carbohydrazide based NK3 receptor antagonists.

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