TTD | Drug: D0W2PK

Drug General Information
Drug ID	D0W2PK
Former ID	DIB015682
Drug Name	Beloxepin
Synonyms	ADL-6906; Beloxepin (oral, pain); Beloxepin (oral, depression), Organon; Beloxepin (oral, pain), Adolor
Indication	Depression [ICD9: 311; ICD10:F30-F39]		Discontinued in Phase 1	[544856]
Company	Adolor Corp; Organon BioSciences
Structure		Download 2D MOL 3D MOL
Canonical SMILES	O1c2c([C@]3([C@H](CN(CC3)C)c3c1c(ccc3)C)O)cccc2
CAS Number	CAS 135928-30-2
Target and Pathway
Target(s)	5-HT 2 receptor	Target Info	Modulator	[550142]
KEGG Pathway	Calcium signaling pathway
	Neuroactive ligand-receptor interaction
	Gap junction
	Serotonergic synapse
	Inflammatory mediator regulation of TRP channels
References
Ref 544856	Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800001334)
Ref 550142	WO patent application no. 2009,1055,07, Beloxepin, its enantiomers, and analogs thereof for the treatment of pain.

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Drug Information