Drug Information

Drug General Information
Drug ID
D0V6YT
Former ID
DIB013682
Drug Name
SR-33805A
Synonyms
3-Isopropyl-2-[4-[3-[N-[2-(3,4-dimethoxyphenyl)ethyl]-N-methylamino]propoxy]phenylsulfonyl]-1-methylindole oxalate
Drug Type
Small molecular drug
Indication Hypertension [ICD9: 401; ICD10:I10-I16] Investigative [534181], [551871]
Structure
Download
2D MOL

3D MOL
Formula
C34H42N2O9S
Canonical SMILES
CC(C)C1=C(N(C2=CC=CC=C21)C)S(=O)(=O)C3=CC=C(C=C3)OCCCN(<br />C)CCC4=CC(=C(C=C4)OC)OC.C(=O)(C(=O)O)O
InChI
1S/C32H40N2O5S.C2H2O4/c1-23(2)31-27-10-7-8-11-28(27)34(4)32(31)40(35,36)26-15-13-25(14-16-26)39-21-9-19-33(3)20-18-24-12-17-29(37-5)30(22-24)38-6;3-1(4)2(5)6/h7-8,10-17,22-23H,9,18-21H2,1-6H3;(H,3,4)(H,5,6)
InChIKey
MZWPPDAHWIKZID-UHFFFAOYSA-N
CAS Number
CAS 121346-33-6
PubChem Compound ID
21256218
PubChem Substance ID
35684129, 55287739, 91746429, 160839590, 163099391, 163402400, 163846300, 164758846, 204366236, 230781957, 252156111, 252366541, 252479499, 252553111
Target and Pathway
Target(s) Calcium channel Target Info Modulator [534181], [551871]
References
Ref 534181Vascular calcium overload produced by vitamin D3, in rats. Effect of treatment with SR 33805, a novel calcium entry blocker. Cardiovasc Res. 1995 Dec;30(6):1038-43.
Ref 551871Drugs@FDA. U.S. Food and Drug Administration. U.S. Department of Health & Human Services. 2015
Ref 534181Vascular calcium overload produced by vitamin D3, in rats. Effect of treatment with SR 33805, a novel calcium entry blocker. Cardiovasc Res. 1995 Dec;30(6):1038-43.
Ref 551871Drugs@FDA. U.S. Food and Drug Administration. U.S. Department of Health & Human Services. 2015

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