Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D0V4RK
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| Former ID |
DIB016630
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| Drug Name |
DPP-IV inhibitors
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| Synonyms |
DPP-IV inhibitors (type 2 diabetes); DPP-IV inhibitors (type 2 diabetes), Toray
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| Indication | Non-insulin dependent diabetes [ICD10:E11.9] | Investigative | [1] | ||
| Company |
Toray Industries Inc
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| Structure |
|
Download2D MOL |
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| Canonical SMILES |
C1CC(CCO1)(c1nc2ccc(cc2s1)OCCOC)NC(=O)C[C@@H](Cc1cc(c(c<br />c1F)F)F)N
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| Target and Pathway | |||||
| Target(s) | Dipeptidyl peptidase IV | Target Info | Inhibitor | [2] | |
| KEGG Pathway | Protein digestion and absorption | ||||
| NetPath Pathway | IL2 Signaling Pathway | ||||
| TGF_beta_Receptor Signaling Pathway | |||||
| References | |||||
| REF 1 | Novel series of 3-amino-N-(4-aryl-1,1-dioxothian-4-yl)butanamides as potent and selective dipeptidyl peptidase IV inhibitors. Bioorg Med Chem Lett. 2012 Dec 1;22(23):7036-40 | ||||
| REF 2 | (http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 1612). | ||||
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