Drug Information

Drug General Information
Drug ID
D0V4MB
Former ID
DCL000619
Drug Name
Remogliflozin etabonate
Synonyms
GSK-189075; GSK-189075A; KGT-1681
Drug Type
Small molecular drug
Indication Type 1/2 diabetes [ICD9: 250, 278; ICD10:E08-E13] Phase 2 [548088]
Company
GSK
Structure
Download
2D MOL

3D MOL
Formula
C26H38N2O9
Canonical SMILES
CCOC(=O)OCC1C(C(C(C(O1)OC2=NN(C(=C2CC3=CC=C(C=C3)OC(C)C<br />)C)C(C)C)O)O)O
InChI
1S/C26H38N2O9/c1-7-33-26(32)34-13-20-21(29)22(30)23(31)25(36-20)37-24-19(16(6)28(27-24)14(2)3)12-17-8-10-18(11-9-17)35-15(4)5/h8-11,14-15,20-23,25,29-31H,7,12-13H2,1-6H3/t20-,21-,22+,23-,25+/m1/s1
InChIKey
UAOCLDQAQNNEAX-ABMICEGHSA-N
CAS Number
CAS 442201-24-3
PubChem Compound ID
9871420
PubChem Substance ID
14836433, 15230843, 24162025, 45293679, 80028622, 87550984, 135252958, 135626775, 140918530, 160672999, 198937387, 223258884, 223860501, 227010458, 242835317
Target and Pathway
Target(s) Sodium/glucose cotransporter 2 Target Info Blocker [550963]
Reactome Hexose transport
Na+-dependent glucose transporters
Inositol transporters
WikiPathways NRF2 pathway
References
Ref 548088Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800021813)
Ref 550963Clinical pipeline report, company report or official report of GlaxoSmithKline (2009).

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