Drug Information
Drug General Information | |||||
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Drug ID |
D0V0NL
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Former ID |
DNC000203
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Drug Name |
Aminoguanidine
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Drug Type |
Small molecular drug
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Structure |
Download2D MOL |
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Formula |
CH6N4
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InChI |
InChI=1S/CH6N4/c2-1(3)5-4/h4H2,(H4,2,3,5)
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InChIKey |
HAMNKKUPIHEESI-UHFFFAOYSA-N
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CAS Number |
CAS 79-17-4
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PubChem Compound ID | |||||
PubChem Substance ID |
613675, 4656528, 7885775, 8151457, 10536095, 11110767, 11110768, 11113705, 12014685, 15170355, 16447240, 26717094, 26758204, 29221325, 30387223, 37457865, 38636745, 42873743, 46506441, 47216879, 47736599, 48110553, 49974251, 50104571, 50104572, 50807510, 53788780, 57321170, 87322642, 88824429, 90341334, 90341800, 103513944, 103825641, 104084871, 104299739, 117516744, 124749450, 124879244, 124879245, 124879246, 125334778, 126546077, 127649709, 128032796, 129532113, 129852663, 134339310, 134339703, 134340037
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Target and Pathway | |||||
Target(s) | Nitric oxide synthase, inducible | Target Info | Inhibitor | [537573] | |
BioCyc Pathway | Citrulline-nitric oxide cycle | ||||
KEGG Pathway | Arginine biosynthesis | ||||
Arginine and proline metabolism | |||||
Metabolic pathways | |||||
Calcium signaling pathway | |||||
HIF-1 signaling pathway | |||||
Peroxisome | |||||
Salmonella infection | |||||
Pertussis | |||||
Leishmaniasis | |||||
Chagas disease (American trypanosomiasis) | |||||
Toxoplasmosis | |||||
Amoebiasis | |||||
Tuberculosis | |||||
Pathways in cancer | |||||
Small cell lung cancer | |||||
NetPath Pathway | IL1 Signaling Pathway | ||||
IL2 Signaling Pathway | |||||
References | |||||
Ref 468198 | (http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 5135). | ||||
Ref 521693 | ClinicalTrials.gov (NCT00184990) Effect of Selective iNOS Inhibition During Human Endotoxemia. U.S. National Institutes of Health. |
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