Drug Information
Drug General Information | |||||
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Drug ID |
D0TU7V
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Former ID |
DIB014783
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Drug Name |
MB-12066
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Synonyms |
B-lapachone (obesity), Mazence; Beta-lapachone (obesity), Mazence
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Indication | Obesity [ICD9: 278; ICD10:E66] | Phase 2 | [524589] | ||
Company |
Mazence Inc
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Target and Pathway | |||||
Target(s) | NAD-dependent deacetylase sirtuin-1 | Target Info | Modulator | ||
PANTHER Pathway | p53 pathway | ||||
Pathway Interaction Database | p73 transcription factor network | ||||
Signaling events mediated by HDAC Class III | |||||
E2F transcription factor network | |||||
HIF-2-alpha transcription factor network | |||||
Signaling events mediated by HDAC Class I | |||||
FoxO family signaling | |||||
Regulation of Androgen receptor activity | |||||
Regulation of retinoblastoma protein | |||||
References |
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