Drug General Information
Drug ID
D0T8TS
Former ID
DNC011735
Drug Name
Hexanoic acid 2,5-diphenyl-thiazol-4-yl ester
Drug Type
Small molecular drug
Indication Discovery agent Investigative [531065]
Structure
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2D MOL

3D MOL

Formula
C21H21NO2S
Canonical SMILES
CCCCCC(=O)OC1=C(SC(=N1)C2=CC=CC=C2)C3=CC=CC=C3
InChI
1S/C21H21NO2S/c1-2-3-6-15-18(23)24-20-19(16-11-7-4-8-12-16)25-21(22-20)17-13-9-5-10-14-17/h4-5,7-14H,2-3,6,15H2,1H3
InChIKey
HQKAVFKKTZEFLJ-UHFFFAOYSA-N
PubChem Compound ID
Target and Pathway
Target(s) Arachidonate 5-lipoxygenase Target Info Inhibitor [531065]
BioCyc Pathway Aspirin-triggered lipoxin biosynthesis
Resolvin D biosynthesis
Leukotriene biosynthesis
Lipoxin biosynthesis
Aspirin triggered resolvin D biosynthesis
Aspirin triggered resolvin E biosynthesis
KEGG Pathway Arachidonic acid metabolism
Metabolic pathways
Serotonergic synapse
Ovarian steroidogenesis
Toxoplasmosis
NetPath Pathway IL4 Signaling Pathway
PathWhiz Pathway Arachidonic Acid Metabolism
WikiPathways Vitamin D Receptor Pathway
Arachidonic acid metabolism
Eicosanoid Synthesis
Selenium Micronutrient Network
References
Ref 531065J Med Chem. 1991 Jul;34(7):2158-65.4-hydroxythiazole inhibitors of 5-lipoxygenase.
Ref 531065J Med Chem. 1991 Jul;34(7):2158-65.4-hydroxythiazole inhibitors of 5-lipoxygenase.

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