Drug Information

Drug General Information
Drug ID
D0T8HU
Former ID
DIB009585
Drug Name
LU-29252
Indication Anxiety disorder [ICD9: 300, 311; ICD10:F32, F40-F42] Terminated [545515]
Company
H Lundbeck A/S
Target and Pathway
Target(s) Sigma(1)-type opioid receptor Target Info Modulator [525460], [526642], [532713]
WikiPathways miR-targeted genes in squamous cell - TarBase
miR-targeted genes in lymphocytes - TarBase
References
Ref 545515Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800003571)
Ref 525460Involvement of sigma receptors in the modulation of the glutamatergic/NMDA neurotransmission in the dopaminergic systems. Eur J Pharmacol. 1999 Mar 5;368(2-3):183-96.
Ref 526642Dextromethorphan antagonizes the acute depletion of brain serotonin by p-chloroamphetamine and H75/12 in rats. Brain Res. 1992 Oct 30;594(2):323-6.
Ref 532713Antitussives and substance abuse. Subst Abuse Rehabil. 2013 Nov 6;4:75-82.

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