Drug General Information
Drug ID
D0T2QN
Former ID
DIB010174
Drug Name
PF-2393296
Synonyms
IDDBCP185108
Indication Neuropathic pain [ICD9: 356.0, 356.8; ICD10:G64, G90.0] Discontinued in Phase 1 [548716]
Company
Pfizer Inc
Structure
Download
2D MOL

3D MOL

Canonical SMILES
C1N[C@@H](C[C@@H]1Cc1cccc(c1)F)C(=O)O
Target and Pathway
Target(s) GABA A receptor delta subunit Target Info Agonist [543815]
KEGG Pathway Neuroactive ligand-receptor interaction
Retrograde endocannabinoid signaling
GABAergic synapse
Morphine addiction
Nicotine addiction
References
Ref 548716Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800027949)
Ref 543815(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 416).

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