Drug Information
Drug General Information | |||||
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Drug ID |
D0SV6C
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Former ID |
DNC010199
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Drug Name |
PRONTOCIL
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Drug Type |
Small molecular drug
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Indication | Discovery agent | Investigative | [529030] | ||
Structure |
Download2D MOL |
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Formula |
C18H16N4O10S3
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Canonical SMILES |
CC(=O)NC1=C(C=C2C=C(C(=NNC3=CC=C(C=C3)S(=O)(=O)N)C(=O)C<br />2=C1)S(=O)(=O)O)S(=O)(=O)O
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InChI |
1S/C18H16N4O10S3/c1-9(23)20-14-8-13-10(6-15(14)34(27,28)29)7-16(35(30,31)32)17(18(13)24)22-21-11-2-4-12(5-3-11)33(19,25)26/h2-8,21H,1H3,(H,20,23)(H2,19,25,26)(H,27,28,29)(H,30,31,32)/b22-17+
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InChIKey |
RFBIZWALEVAHDX-OQKWZONESA-N
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PubChem Compound ID | |||||
Target and Pathway | |||||
Target(s) | Carbonic anhydrase | Target Info | Inhibitor | [529030] | |
Carbonic anhydrase II | Target Info | Inhibitor | [530292] | ||
NetPath Pathway | IL4 Signaling Pathway | ||||
EGFR1 Signaling Pathway | |||||
References | |||||
Ref 529030 | Bioorg Med Chem. 2007 Dec 1;15(23):7229-36. Epub 2007 Aug 25.Carbonic anhydrase inhibitors: cloning, characterization, and inhibition studies of the cytosolic isozyme III with sulfonamides. | ||||
Ref 530292 | Bioorg Med Chem Lett. 2009 Sep 1;19(17):4929-32. Epub 2009 Jul 22.Carbonic anhydrase inhibitors. Inhibition of the Rv1284 and Rv3273 beta-carbonic anhydrases from Mycobacterium tuberculosis with diazenylbenzenesulfonamides. |
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