Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D0SU0Y
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| Former ID |
DNC008639
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| Drug Name |
1-(1-Biphenyl-4-yl-butyl)-1H-imidazole
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent | Investigative | [529625] | ||
| Structure |
|
Download2D MOL |
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| Formula |
C19H20N2
|
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| Canonical SMILES |
CCCC(C1=CC=C(C=C1)C2=CC=CC=C2)N3C=CN=C3
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| InChI |
1S/C19H20N2/c1-2-6-19(21-14-13-20-15-21)18-11-9-17(10-12-18)16-7-4-3-5-8-16/h3-5,7-15,19H,2,6H2,1H3
|
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| InChIKey |
SLKWPFBZPUBKHY-UHFFFAOYSA-N
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| PubChem Compound ID | |||||
| Target and Pathway | |||||
| Target(s) | 17 alpha-hydroxylase-C17, 20-lyase | Target Info | Inhibitor | [529625] | |
| PathWhiz Pathway | Androgen and Estrogen Metabolism | ||||
| Steroidogenesis | |||||
| References | |||||
| Ref 529625 | Bioorg Med Chem. 2008 Aug 15;16(16):7715-27. Epub 2008 Jul 9.Synthesis, biological evaluation, and molecular modeling studies of methylene imidazole substituted biaryls as inhibitors of human 17alpha-hydroxylase-17,20-lyase (CYP17)--part II: Core rigidification and influence of substituents at the methylene bridge. | ||||
| Ref 529625 | Bioorg Med Chem. 2008 Aug 15;16(16):7715-27. Epub 2008 Jul 9.Synthesis, biological evaluation, and molecular modeling studies of methylene imidazole substituted biaryls as inhibitors of human 17alpha-hydroxylase-17,20-lyase (CYP17)--part II: Core rigidification and influence of substituents at the methylene bridge. | ||||
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