Drug General Information
Drug ID
D0ST5P
Former ID
DIB000411
Drug Name
TA-5538
Synonyms
IDDBCP232835
Indication Overactive bladder disorder [ICD9: 188, 596.51; ICD10:C67, N32.81] Discontinued in Phase 2 [548065]
Company
Tanabe Seiyaku Co Ltd
Structure
Download
2D MOL

3D MOL

Canonical SMILES
N1([C@H](C[C@H](CC1)OC(=O)NCCO)c1c(cc(cc1)F)C)C(=O)N(C)<br />Cc1cc(cc(c1)C(F)(F)F)C(F)(F)F
Target and Pathway
Target(s) Substance-P receptor Target Info Antagonist [548066]
KEGG Pathway Calcium signaling pathway
Neuroactive ligand-receptor interaction
Measles
PANTHER Pathway CCKR signaling map ST
Reactome G alpha (q) signalling events
WikiPathways SIDS Susceptibility Pathways
Gastrin-CREB signalling pathway via PKC and MAPK
Spinal Cord Injury
Peptide GPCRs
GPCR ligand binding
GPCR downstream signaling
References
Ref 548065Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800021639)
Ref 548066Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800021639)

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