Drug Information

Drug General Information
Drug ID
D0S2IQ
Former ID
DNAP001441
Drug Name
Sapropterin hydrochloride
Synonyms
Biopten (TN)
Drug Type
Small molecular drug
Indication Hyperphenylalaninemia [ICD10:E70.1] Approved [529282]
Structure
Download
2D MOL

3D MOL
Formula
C9H17Cl2N5O3
Canonical SMILES
CC(C(C1CNC2=C(N1)C(=O)N=C(N2)N)O)O.Cl.Cl
InChI
1S/C9H15N5O3.2ClH/c1-3(15)6(16)4-2-11-7-5(12-4)8(17)14-9(10)13-7;;/h3-4,6,12,15-16H,2H2,1H3,(H4,10,11,13,14,17);2*1H/t3-,4+,6-;;/m0../s1
InChIKey
RKSUYBCOVNCALL-NTVURLEBSA-N
PubChem Compound ID
636369
PubChem Substance ID
3153183, 7848860, 11601506, 12014491, 14776738, 14801109, 24277922, 43758872, 56311539, 57407191, 75487273, 91722512, 93581336, 103771501, 113523785, 126685033, 135131482, 137249803, 144205335, 160820722, 162249508, 163091204, 163379274, 164340397, 164827597, 175268612, 223678991, 226607428, 241121735, 250210464, 252237154, 252425064
SuperDrug ATC ID
A16AX07
Target and Pathway
Target(s) Phenylalanine hydroxylase Target Info Modulator [529282]
BioCyc Pathway Phenylalanine degradation/tyrosine biosynthesis
KEGG Pathway Phenylalanine metabolism
Phenylalanine, tyrosine and tryptophan biosynthesis
Metabolic pathways
Biosynthesis of amino acids
PathWhiz Pathway Phenylalanine and Tyrosine Metabolism
WikiPathways SIDS Susceptibility Pathways
Biogenic Amine Synthesis
Metabolism of amino acids and derivatives
Abnormal metabolism in phenylketonuria
References
Ref 5292822007 FDA drug approvals: a year of flux. Nat Rev Drug Discov. 2008 Feb;7(2):107-9.
Ref 5292822007 FDA drug approvals: a year of flux. Nat Rev Drug Discov. 2008 Feb;7(2):107-9.

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