Drug Information

Drug General Information
Drug ID
D0S0NB
Former ID
DIB021110
Drug Name
UCCF-853
Drug Type
Small molecular drug
Indication Discovery agent Investigative [467676]
Structure
Download
2D MOL
Formula
C14H8ClF3N2O
InChI
InChI=1S/C14H8ClF3N2O/c15-9-2-1-3-10(7-9)20-12-5-4-8(14(16,17)18)6-11(12)19-13(20)21/h1-7H,(H,19,21)
InChIKey
NMPJFFWYEIIGFW-UHFFFAOYSA-N
PubChem Compound ID
17750928
PubChem Substance ID
29203547, 29585110, 47156973, 125503163, 134964009, 162117920, 172819513, 178101155, 240030160, 245512448
Target and Pathway
Target(s) cystic fibrosis transmembrane conductance regulator Target Info Activator [543927]
KEGG Pathway ABC transporters
cAMP signaling pathway
AMPK signaling pathway
Gastric acid secretion
Pancreatic secretion
Bile secretion
Vibrio cholerae infection
Reactome ABC-family proteins mediated transport
WikiPathways ABC-family proteins mediated transport
References
Ref 467676(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 4338).
Ref 543927(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 707).

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