Drug Information

Drug General Information
Drug ID
D0RG2P
Former ID
DNC012378
Drug Name
SC-50560
Drug Type
Small molecular drug
Indication Discovery agent Terminated [545548]
Structure
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2D MOL

3D MOL
Formula
C24H29N7
Canonical SMILES
CCCCC1=NN(C(=N1)CCCC)CC2=CC=C(C=C2)C3=CC=CC=C3C4=NNN=N4
InChI
1S/C24H29N7/c1-3-5-11-22-25-23(12-6-4-2)31(28-22)17-18-13-15-19(16-14-18)20-9-7-8-10-21(20)24-26-29-30-27-24/h7-10,13-16H,3-6,11-12,17H2,1-2H3,(H,26,27,29,30)
InChIKey
LRZYXWIVLLNUPK-UHFFFAOYSA-N
PubChem Compound ID
9931685
Target and Pathway
Target(s) Type-2 angiotensin II receptor Target Info Inhibitor [551257]
KEGG Pathway Neuroactive ligand-receptor interaction
Adrenergic signaling in cardiomyocytes
Renin-angiotensin system
Reactome Peptide ligand-binding receptors
G alpha (i) signalling events
WikiPathways ACE Inhibitor Pathway
GPCRs, Class A Rhodopsin-like
Peptide GPCRs
GPCR ligand binding
GPCR downstream signaling
References
Ref 545548Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800003674)
Ref 551257N1-sterically hindered 2H-imidazol-2-one angiotensin II receptor antagonists: The conversion of surmountable antagonists to insurmountable antagonists, Bioorg. Med. Chem. Lett. 3(6):1055-1060 (1993).

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