Drug Information

Drug General Information
Drug ID
D0R9CC
Former ID
DIB019039
Drug Name
BW 245C
Synonyms
BW245C; BW-245C
Drug Type
Small molecular drug
Indication Discovery agent Investigative [539178]
Structure
Download
2D MOL
Formula
C19H32N2O5
InChI
InChI=1S/C19H32N2O5/c22-16(14-8-4-3-5-9-14)12-13-21-15(18(25)20-19(21)26)10-6-1-2-7-11-17(23)24/h14-16,22H,1-13H2,(H,23,24)(H,20,25,26)
InChIKey
ZIDQIOZJEJFMOH-UHFFFAOYSA-N
PubChem Compound ID
119304
PubChem Substance ID
855546, 7978834, 10238435, 12012779, 29300213, 53790818, 56463777, 57339428, 80825512, 85208990, 103139751, 103698624, 104408008, 117548657, 117613087, 124801120, 124879455, 125334177, 135073565, 135650040, 162654837, 178125577, 179151035, 179504348, 224828623, 234887228, 241132110
Target and Pathway
Target(s) Prostaglandin D2 receptor Target Info Agonist [534478]
KEGG Pathway Neuroactive ligand-receptor interaction
Pathway Interaction Database Thromboxane A2 receptor signaling
PathWhiz Pathway Intracellular Signalling Through PGD2 receptor and Prostaglandin D2
Reactome Prostanoid ligand receptors
G alpha (s) signalling events
WikiPathways Prostaglandin Synthesis and Regulation
GPCRs, Class A Rhodopsin-like
Small Ligand GPCRs
GPCR ligand binding
GPCR downstream signaling
References
Ref 539178(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 1878).
Ref 534478Ligand binding specificities of the eight types and subtypes of the mouse prostanoid receptors expressed in Chinese hamster ovary cells. Br J Pharmacol. 1997 Sep;122(2):217-24.

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