Drug Information
Drug General Information | |||||
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Drug ID |
D0R8IE
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Former ID |
DIB015725
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Drug Name |
Inecalcitol oral
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Synonyms |
Inecalcitol; TX-522; TX-527; Vitamin D analogs, Catholic University of Leuven; Vitamin D analogs, KULeuven; Inecalcitol (oral, hyperthyroidism), Hybrigenics; Inecalcitol (sc, psoriasis), Hybrigenics; Vitamin D analog (sc, psoriasis), Hybrigenics; Inecalcitol (oral, prostate cancer/psoriasis), Hybrigenics
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Drug Type |
Small molecular drug
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Company |
Catholic University of Leuven; Hybrigenics
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Structure |
Download2D MOL |
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Formula |
C26H40O3
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InChI |
InChI=1S/C26H40O3/c1-18(7-5-13-25(2,3)29)23-11-12-24-20(8-6-14-26(23,24)4)10-9-19-15-21(27)17-22(28)16-19/h9-10,18,21-24,27-29H,6-8,11-12,14-17H2,1-4H3/b20-10+/t18-,21-,22-,23-,24-,26-/m1/s1
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InChIKey |
HHGRMHMXKPQNGF-WNSNRMDMSA-N
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CAS Number |
CAS 163217-09-2
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PubChem Compound ID | |||||
PubChem Substance ID | |||||
Target and Pathway | |||||
Target(s) | Vitamin D receptor | Target Info | Agonist | [532222] | |
NetPath Pathway | IL4 Signaling Pathway | ||||
PANTHER Pathway | Vitamin D metabolism and pathway | ||||
References | |||||
Ref 532222 | Inecalcitol, an analog of 1,25D3, displays enhanced antitumor activity through the induction of apoptosis in a squamous cell carcinoma model system. Cell Cycle. 2013 Mar 1;12(5):743-52. | ||||
Ref 542712 | (http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 7747). |
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