Drug Information

Drug General Information
Drug ID
D0R7AK
Former ID
DIB014382
Drug Name
CP-601927
Synonyms
CP-601932; Alpha4beta2 nAchR partial agonists (depression), Pfizer
Drug Type
Small molecular drug
Indication Gastrointestinal disease [ICD10:K00-K93] Phase 2 [522995]
Company
Pfizer Inc
Structure
Download
2D MOL

3D MOL
Formula
C12H12F3N
Canonical SMILES
C1C2CNCC1C3=C2C=CC(=C3)C(F)(F)F
InChI
1S/C12H12F3N/c13-12(14,15)9-1-2-10-7-3-8(6-16-5-7)11(10)4-9/h1-2,4,7-8,16H,3,5-6H2/t7-,8+/m1/s1
InChIKey
RNOBTWYQAWEZHH-SFYZADRCSA-N
PubChem Compound ID
69604735
PubChem Substance ID
172113635, 198952456, 231688680, 248763804
Target and Pathway
Target(s) Nicotinic ACh receptor alpha 4/beta 2 Target Info Modulator [531488]
References
Ref 522995ClinicalTrials.gov (NCT01098240) A Study Of The Efficacy And Safety Of CP-601,927 Augmentation Of Antidepressant Therapy In Major Depression. U.S. National Institutes of Health.
Ref 531488Toxicity study in juvenile rats with the alpha4beta2 nicotinic acetylcholine receptor partial agonist CP-601,927. Birth Defects Res B Dev Reprod Toxicol. 2011 Aug;92(4):323-32.

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