Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D0R5AU
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| Former ID |
DIB007462
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| Drug Name |
LASINAVIR
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| Synonyms |
BMS-234475; CGP-61755; Lasinavir < Prop INN >; N-[5(S)-(tert-Butoxycarbonylamino)-4(S)-hydroxy-6-phenyl-2(R)-(2,3,4-trimethoxybenzyl)hexanoyl]-L-valine 2-methoxyethylamide
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| Drug Type |
Small molecular drug
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| Indication | Human immunodeficiency virus infection [ICD9: 279.3; ICD10:B20-B26] | Discontinued in Phase 1 | [546180] | ||
| Structure |
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Download2D MOL |
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| Formula |
C35H53N3O9
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| Canonical SMILES |
COCCNC(=O)[C@@H](NC(=O)[C@@H](C[C@H](O)[C@H](Cc1ccccc1)<br />NC(=O)OC(C)(C)C)Cc2ccc(OC)c(OC)c2OC)C(C)C
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| InChI |
1S/C35H53N3O9/c1-22(2)29(33(41)36-17-18-43-6)38-32(40)25(20-24-15-16-28(44-7)31(46-9)30(24)45-8)21-27(39)26(19-23-13-11-10-12-14-23)37-34(42)47-35(3,4)5/h10-16,22,25-27,29,39H,17-21H2,1-9H3,(H,36,41)(H,37,42)(H,38,40)/t25-,26+,27+,29+/m1/s1
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| InChIKey |
BEUUJDAEPJZWHM-COROXYKFSA-N
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| CAS Number |
CAS 175385-62-3
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| PubChem Compound ID | |||||
| Target and Pathway | |||||
| Target(s) | HIV protease | Target Info | Inhibitor | [534465], [551871] | |
| References | |||||
| Ref 534465 | Quantitative determination of CGP 61755, a protease inhibitor, in plasma and urine by high-performance liquid chromatography and fluorescence detection. J Chromatogr B Biomed Sci Appl. 1997 Aug 15;696(1):123-30. | ||||
| Ref 551871 | Drugs@FDA. U.S. Food and Drug Administration. U.S. Department of Health & Human Services. 2015 | ||||
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