Drug Information

Drug General Information
Drug ID
D0R3PD
Former ID
DNC004220
Drug Name
CLAVARINONE
Drug Type
Small molecular drug
Indication Discovery agent Investigative [534739]
Structure
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2D MOL

3D MOL
Formula
C30H50O4
Canonical SMILES
CC(CCC(C(C)(C)O)O)C1CCC2(C1(CCC3=C2CCC4C3(CC(C(=O)C4(C)<br />C)O)C)C)C
InChI
1S/C30H50O4/c1-18(9-12-24(32)27(4,5)34)19-13-15-30(8)21-10-11-23-26(2,3)25(33)22(31)17-28(23,6)20(21)14-16-29(19,30)7/h18-19,22-24,31-32,34H,9-17H2,1-8H3/t18-,19-,22-,23?,24?,28-,29-,30+/m1/s1
InChIKey
TZXHHXSEUPQHDR-QHMLUVRNSA-N
PubChem Compound ID
44359599
Target and Pathway
Target(s) Protein farnesyltransferase beta subunit Target Info Inhibitor [534739]
Farnesyltransferase Target Info Inhibitor [534739]
KEGG Pathway Terpenoid backbone biosynthesis
Biosynthesis of antibioticshsa00900:Terpenoid backbone biosynthesis
Biosynthesis of antibiotics
NetPath Pathway TSH Signaling Pathway
Reactome Inactivation, recovery and regulation of the phototransduction cascadeR-HSA-111465:Apoptotic cleavage of cellular proteins
Inactivation, recovery and regulation of the phototransduction cascade
WikiPathways Visual phototransductionWP2776:Visual phototransduction
Apoptotic execution phase
References
Ref 534739J Med Chem. 1998 Nov 5;41(23):4492-501.Clavaric acid and steroidal analogues as Ras- and FPP-directed inhibitors of human farnesyl-protein transferase.
Ref 534739J Med Chem. 1998 Nov 5;41(23):4492-501.Clavaric acid and steroidal analogues as Ras- and FPP-directed inhibitors of human farnesyl-protein transferase.

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