Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D0R2HZ
|
||||
| Former ID |
DIB004557
|
||||
| Drug Name |
ETHOXY-IDAZOXAN
|
||||
| Synonyms |
RX-811059; 2-(2-Ethoxy-1,4-benzodioxan-2-yl)-1-imidazoline
|
||||
| Drug Type |
Small molecular drug
|
||||
| Indication | Poison intoxication [ICD10:T36-T50] | Investigative | [1] | ||
| Structure |
|
Download2D MOL |
|||
| Formula |
C13H16N2O3
|
||||
| Canonical SMILES |
CCOC1(COC2=CC=CC=C2O1)C3=NCCN3
|
||||
| InChI |
1S/C13H16N2O3/c1-2-17-13(12-14-7-8-15-12)9-16-10-5-3-4-6-11(10)18-13/h3-6H,2,7-9H2,1H3,(H,14,15)
|
||||
| InChIKey |
PXTLRBYNGGDZBN-UHFFFAOYSA-N
|
||||
| CAS Number |
CAS 96576-24-8
|
||||
| PubChem Compound ID | |||||
| PubChem Substance ID | |||||
| Target and Pathway | |||||
| Target(s) | Alpha-2C adrenergic receptor | Target Info | Modulator | [1] | |
| KEGG Pathway | cGMP-PKG signaling pathway | ||||
| Neuroactive ligand-receptor interaction | |||||
| PANTHER Pathway | Alpha adrenergic receptor signaling pathway | ||||
| Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway | |||||
| Reactome | Adrenoceptors | ||||
| Adrenaline signalling through Alpha-2 adrenergic receptor | |||||
| Adrenaline,noradrenaline inhibits insulin secretion | |||||
| G alpha (i) signalling events | |||||
| G alpha (z) signalling events | |||||
| Surfactant metabolism | |||||
| WikiPathways | Monoamine GPCRs | ||||
| GPCRs, Class A Rhodopsin-like | |||||
| Platelet Aggregation (Plug Formation) | |||||
| Integration of energy metabolism | |||||
| GPCR ligand binding | |||||
| GPCR downstream signaling | |||||
| References | |||||
| REF 1 | Discriminative stimulus properties of ethoxy idazoxan. J Psychopharmacol. 1995 Jan;9(3):228-33. | ||||
If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.