Drug General Information
Drug ID	D0R2HJ
Former ID	DNC012305
Drug Name	Isoquinoline-3-carboxylic acid methyl ester
Drug Type	Small molecular drug
Indication	Discovery agent		Investigative	[533363]
Structure		Download 2D MOL 3D MOL
Formula	C11H9NO2
Canonical SMILES	COC(=O)C1=CC2=CC=CC=C2C=N1
InChI	1S/C11H9NO2/c1-14-11(13)10-6-8-4-2-3-5-9(8)7-12-10/h2-7H,1H3
InChIKey	ZBCGBIZQNMVMPC-UHFFFAOYSA-N
PubChem Compound ID	725374
Target and Pathway
Target(s)	Gamma-aminobutyric acid receptor subunit alpha-1	Target Info	Inhibitor	[533363]
	Gamma-aminobutyric acid receptor	Target Info	Inhibitor	[533363]
KEGG Pathway	Neuroactive ligand-receptor interaction
	Retrograde endocannabinoid signaling
	GABAergic synapse
	Morphine addiction
	Nicotine addiction
Reactome	Ligand-gated ion channel transport
	GABA A receptor activation
WikiPathways	SIDS Susceptibility Pathways
	Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell
	Iron uptake and transport
References
Ref 533363	J Med Chem. 1988 Sep;31(9):1854-61.Synthesis of novel 3-substituted beta-carbolines as benzodiazepine receptor ligands: probing the benzodiazepine receptor pharmacophore.
Ref 533363	J Med Chem. 1988 Sep;31(9):1854-61.Synthesis of novel 3-substituted beta-carbolines as benzodiazepine receptor ligands: probing the benzodiazepine receptor pharmacophore.

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