Drug Information
Drug General Information | |||||
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Drug ID |
D0Q9EV
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Drug Name |
lifitegrast
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Synonyms |
SAR-1118; SAR-1119; SHP606; SPD606; Xiidra
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Drug Type |
Small molecular drug
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Indication | Dry eye disease [ICD9: 370.33; ICD10:H16.229] | Approved | [889440] | ||
Company |
Shire Pharmaceuticals
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Structure |
Download2D MOL |
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Formula |
C29H24Cl2N2O7S
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PubChem Compound ID | |||||
Target and Pathway | |||||
Target(s) | Lymphocyte function-associated antigen 1 | Target Info | Modulator | [889440] | |
KEGG Pathway | Rap1 signaling pathway | ||||
Cell adhesion molecules (CAMs) | |||||
Natural killer cell mediated cytotoxicity | |||||
Leukocyte transendothelial migration | |||||
Regulation of actin cytoskeleton | |||||
Malaria | |||||
Staphylococcus aureus infection | |||||
HTLV-I infection | |||||
Epstein-Barr virus infection | |||||
Rheumatoid arthritis | |||||
Viral myocarditis | |||||
NetPath Pathway | TCR Signaling Pathway | ||||
RANKL Signaling Pathway | |||||
Pathway Interaction Database | Integrin family cell surface interactions | ||||
Beta2 integrin cell surface interactions | |||||
CXCR3-mediated signaling events | |||||
References |
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