Drug Information

Drug General Information
Drug ID
D0Q8TJ
Former ID
DIB018771
Drug Name
AG-14
Synonyms
AG14; AG 14
Drug Type
Small molecular drug
Indication Discovery agent Investigative [541154]
Structure
Download
2D MOL

3D MOL
Formula
C23H20N2O5
InChI
InChI=1S/C23H20N2O5/c1-27-21-11-17(7-9-19(21)28-14-16-5-3-2-4-6-16)13-24-25-23(26)18-8-10-20-22(12-18)30-15-29-20/h2-13H,14-15H2,1H3,(H,25,26)/b24-13+
InChIKey
ULOKADSYVZOTTL-ZMOGYAJESA-N
PubChem Compound ID
9618971
PubChem Substance ID
24031045, 44754014, 70824967, 76986556, 83581206, 87795353, 104915114, 123096188
Target and Pathway
Target(s) FMLP receptor Target Info Agonist [528624]
KEGG Pathway Rap1 signaling pathway
Neuroactive ligand-receptor interaction
Staphylococcus aureus infection
NetPath Pathway Leptin Signaling Pathway
PANTHER Pathway Inflammation mediated by chemokine and cytokine signaling pathway
Pathway Interaction Database Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
Reactome G alpha (i) signalling events
WikiPathways GPCRs, Class A Rhodopsin-like
Human Complement System
Peptide GPCRs
GPCR ligand binding
GPCR downstream signaling
References
Ref 541154(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 5835).
Ref 528624High-throughput screening for small-molecule activators of neutrophils: identification of novel N-formyl peptide receptor agonists. Mol Pharmacol. 2007 Apr;71(4):1061-74. Epub 2007 Jan 17.

If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.