Drug Information

Drug General Information
Drug ID
D0Q7LD
Former ID
DNC002645
Drug Name
2-Methyl-2-Propanol
Drug Type
Small molecular drug
Indication Discovery agent Investigative [551393]
Structure
Download
2D MOL

3D MOL
Formula
C4H10O
Canonical SMILES
CC(C)(C)O
InChI
1S/C4H10O/c1-4(2,3)5/h5H,1-3H3
InChIKey
DKGAVHZHDRPRBM-UHFFFAOYSA-N
PubChem Compound ID
6386
PubChem Substance ID
587060, 820565, 824488, 824493, 824495, 829409, 831395, 831718, 837274, 854655, 3132278, 6467454, 7890706, 8023088, 8154051, 10534928, 12079254, 14709186, 15146291, 17425442, 24851330, 24858660, 24859879, 24862169, 24867672, 24870757, 24873382, 24892081, 26697099, 26703480, 26706548, 26710884, 26719397, 29225374, 30964600, 37451913, 37609869, 37615327, 46507480, 48409757, 48409762, 48413335, 48414942, 48416814, 48420525, 48424140, 49854267, 57309692, 57323401, 57410735
Target and Pathway
Target(s) Calmodulin Target Info Inhibitor [551393]
Methionine aminopeptidase 2 Target Info Inhibitor [551393]
KEGG Pathway Ras signaling pathway
Rap1 signaling pathway
Calcium signaling pathway
cGMP-PKG signaling pathway
cAMP signaling pathway
Phosphatidylinositol signaling system
Oocyte meiosis
Adrenergic signaling in cardiomyocytes
Vascular smooth muscle contraction
Circadian entrainment
Long-term potentiation
Neurotrophin signaling pathway
Dopaminergic synapse
Olfactory transduction
Phototransduction
Inflammatory mediator regulation of TRP channels
Insulin signaling pathway
GnRH signaling pathway
Estrogen signaling pathway
Melanogenesis
Oxytocin signaling pathway
Glucagon signaling pathway
Salivary secretion
Gastric acid secretion
Alzheimer's disease
Amphetamine addiction
Alcoholism
Pertussis
Tuberculosis
Glioma
NetPath Pathway RANKL Signaling Pathway
TSH Signaling Pathway
PANTHER Pathway CCKR signaling map ST
Pathway Interaction Database BCR signaling pathway
p38 MAPK signaling pathway
Calcineurin-regulated NFAT-dependent transcription in lymphocytes
Role of Calcineurin-dependent NFAT signaling in lymphocytes
IL2 signaling events mediated by PI3K
IFN-gamma pathway
Lissencephaly gene (LIS1) in neuronal migration and development
ErbB1 downstream signaling
VEGFR1 specific signals
Regulation of cytoplasmic and nuclear SMAD2/3 signaling
Calcium signaling in the CD4+ TCR pathway
Signaling events mediated by VEGFR1 and VEGFR2
Insulin-mediated glucose transport
N-cadherin signaling events
Cellular roles of Anthrax toxin
Regulation of Ras family activation
Downstream signaling in na&#xef
PathWhiz Pathway Muscle/Heart Contraction
Reactome Calmodulin induced events
Platelet degranulation
Translocation of GLUT4 to the plasma membrane
Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
DARPP-32 events
eNOS activation
Inactivation, recovery and regulation of the phototransduction cascade
FCERI mediated Ca+2 mobilization
Ca2+ pathway
CREB phosphorylation through the activation of CaMKII
Ras activation uopn Ca2+ infux through NMDA receptor
Smooth Muscle Contraction
VEGFR2 mediated vascular permeability
VEGFR2 mediated cell proliferation
RHO GTPases activate IQGAPs
RAF/MAP kinase cascade
Antigen activates B Cell Receptor (BCR) leading to generation of second messengersR-HSA-2514859:Inactivation, recovery and regulation of the phototransduction cascade
WikiPathways Translocation of GLUT4 to the Plasma Membrane
Visual phototransduction
Fc epsilon receptor (FCERI) signaling
Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell
Signaling by the B Cell Receptor (BCR)
Inositol phosphate metabolism
DAG and IP3 signaling
Opioid Signalling
Muscle contraction
Metabolism of nitric oxide
Metabolism of carbohydrates
References
Ref 551393How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6.
Ref 551393How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6.

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