Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D0Q6PI
|
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| Former ID |
DNC012267
|
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| Drug Name |
PHENETHYLAMINE
|
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| Drug Type |
Small molecular drug
|
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| Indication | Discovery agent | Investigative | [1] | ||
| Structure |
|
Download2D MOL |
|||
| Formula |
C8H11N
|
||||
| InChI |
InChI=1S/C8H11N/c9-7-6-8-4-2-1-3-5-8/h1-5H,6-7,9H2
|
||||
| InChIKey |
BHHGXPLMPWCGHP-UHFFFAOYSA-N
|
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| CAS Number |
CAS 64-04-0
|
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| PubChem Compound ID | |||||
| PubChem Substance ID |
7711, 75923, 608001, 833519, 833521, 839990, 3135776, 5482019, 8144848, 8150920, 10509252, 10531461, 14747570, 24847881, 24854450, 24865438, 24865867, 24887854, 24887855, 24901561, 26756723, 30280509, 32040725, 33286030, 36523320, 46393246, 46393335, 46393337, 47193684, 49661414, 49718670, 49856894, 57320659, 57652878, 57652879, 75745031, 80953779, 85165171, 87574348, 88519487, 92298625, 92729694, 103185023, 103812726, 104296483, 104667507, 117531353, 117531423, 118307932, 124811907
|
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| Target and Pathway | |||||
| Target(s) | 5-hydroxytryptamine 2A receptor | Target Info | Inhibitor | [2] | |
| KEGG Pathway | Calcium signaling pathway | ||||
| Neuroactive ligand-receptor interaction | |||||
| Gap junction | |||||
| Serotonergic synapse | |||||
| Inflammatory mediator regulation of TRP channels | |||||
| PANTHER Pathway | 5HT2 type receptor mediated signaling pathway | ||||
| Reactome | Serotonin receptors | ||||
| G alpha (q) signalling events | |||||
| WikiPathways | Serotonin Receptor 2 and STAT3 Signaling | ||||
| Serotonin Receptor 2 and ELK-SRF/GATA4 signaling | |||||
| SIDS Susceptibility Pathways | |||||
| Monoamine GPCRs | |||||
| GPCRs, Class A Rhodopsin-like | |||||
| Gastrin-CREB signalling pathway via PKC and MAPK | |||||
| GPCR ligand binding | |||||
| GPCR downstream signaling | |||||
| GPCRs, Other | |||||
| References | |||||
| REF 1 | (http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 2144). | ||||
| REF 2 | Bioorg Med Chem Lett. 2001 Feb 26;11(4):563-6.Exploring the relationship between binding modes of 9-(aminomethyl)-9,10-dihydroanthracene and cyproheptadine analogues at the 5-HT2A serotonin receptor. | ||||
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