Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D0Q6IW
|
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| Former ID |
DCL000632
|
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| Drug Name |
Rosiglitazone + simvastatin
|
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| Drug Type |
Small molecular drug
|
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| Indication | Type 2 diabetes [ICD9: 250; ICD10:E11] | Phase 3 | [550971] | ||
| Company |
GSK
|
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| Structure |
|
Download2D MOL |
|||
| Formula |
C13H11N3O2
|
||||
| Canonical SMILES |
COC1=CC2=C(C=C1)NC(=O)C2=CC3C=NC=N3
|
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| InChI |
1S/C13H11N3O2/c1-18-9-2-3-12-10(5-9)11(13(17)16-12)4-8-6-14-7-15-8/h2-8H,1H3,(H,16,17)/b11-4-
|
||||
| InChIKey |
KKGJVFQBVRACGR-WCIBSUBMSA-N
|
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| CAS Number |
CAS 122320-73-4
|
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| PubChem Compound ID | |||||
| PubChem Substance ID | |||||
| Target and Pathway | |||||
| Target(s) | Peroxisome proliferator activated receptor gamma | Target Info | Agonist | [550963] | |
| PANTHER Pathway | CCKR signaling map ST | ||||
| WikiPathways | Wnt Signaling Pathway Netpath | ||||
| Nuclear Receptors in Lipid Metabolism and Toxicity | |||||
| Differentiation of white and brown adipocyte | |||||
| Regulation of Lipid Metabolism by Peroxisome proliferator-activated receptor alpha (PPARalpha) | |||||
| Transcriptional Regulation of White Adipocyte Differentiation | |||||
| Adipogenesis | |||||
| SREBP signalling | |||||
| Nuclear Receptors | |||||
| References | |||||
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