Drug Information
Drug General Information | |||||
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Drug ID |
D0Q0YS
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Former ID |
DIB020865
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Drug Name |
rT3
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Synonyms |
reverse T3; reverse triiodothyronine
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Drug Type |
Small molecular drug
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Indication | Discovery agent | Investigative | [539701] | ||
Structure |
Download2D MOL |
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Formula |
C15H12I3NO4
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InChI |
InChI=1S/C15H12I3NO4/c16-9-3-7(4-12(19)15(21)22)1-2-13(9)23-8-5-10(17)14(20)11(18)6-8/h1-3,5-6,12,20H,4,19H2,(H,21,22)
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InChIKey |
HZCBWYNLGPIQRK-UHFFFAOYSA-N
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PubChem Compound ID | |||||
PubChem Substance ID | |||||
Target and Pathway | |||||
Target(s) | Thyroid hormone receptor alpha | Target Info | Agonist | [531482] | |
Thyroid hormone receptor beta-1 | Target Info | Agonist | [531482] | ||
References | |||||
Ref 531482 | Binding of 3,5,3'-triiodothyronine (T3) and its analogs to the in vitro translational products of c-erbA protooncogenes: differences in the affinity of the alpha- and beta-forms for the acetic acid analog and failure of the human testis and kidney alpha-2 products to bind T3. Mol Endocrinol. 1990 Feb;4(2):227-34. |
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