Drug Information
Drug General Information | |||||
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Drug ID |
D0PG0G
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Former ID |
DAP000151
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Drug Name |
Drotrecogin alfa
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Synonyms |
Xigris; Drotrecogin alfa (activated); Xigris (TN); Drotrecogin alfa (activated) (USAN)
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Therapeutic Class |
Antisepsis Agents
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Company |
Eli Lilly
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Formula |
C1786H2779N509O519S29
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CAS Number |
CAS 60202-16-6
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PubChem Substance ID | |||||
SuperDrug ATC ID |
B01AD10
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Target and Pathway | |||||
Target(s) | Coagulation Factor VIIIa | Target Info | Inhibitor | [537427] | |
Coagulation Factor Va | Target Info | Inhibitor | [537427] | ||
PANTHER Pathway | Blood coagulation | ||||
PathWhiz Pathway | CoagulationPW000562:Coagulation | ||||
References | |||||
Ref 536361 | Natural products as sources of new drugs over the last 25 years. J Nat Prod. 2007 Mar;70(3):461-77. Epub 2007 Feb 20. | ||||
Ref 541868 | (http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 6788). | ||||
Ref 551871 | Drugs@FDA. U.S. Food and Drug Administration. U.S. Department of Health & Human Services. 2015 |
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