Drug General Information
Drug ID
D0P8TS
Former ID
DIB001782
Drug Name
Eperisone
Synonyms
EMPP; Myonal; Myorelark; E-0646; E-2000; E-646; Eperisone (transdermal patch); Eperisone (oral), Eisai; Eperisone (transdermalpatch), Eisai; E-2000 (oral), Eisai; E-2000 (transdermal patch), Eisai
Drug Type
Small molecular drug
Indication Muscle spasm [ICD10:M62.838] Phase 3 [524606]
Company
Eisai Co Ltd
Structure
Download
2D MOL

3D MOL

Formula
C17H26ClNO
Canonical SMILES
C(=O)(C(CN1CCCCC1)C)c1ccc(cc1)CC
PubChem Compound ID
Target and Pathway
Target(s) Voltage-dependent calcium channel Target Info Modulator [530122], [533095]
References
Ref 524606ClinicalTrials.gov (NCT02040415) Phase 3 Study to Evaluate the Efficacy and Safety of DW-1030 and Eperisone HCl in Acute Back Pain Patients. U.S. National Institutes of Health.
Ref 530122Inhibitory effect of glutamate release from rat cerebrocortical synaptosomes by dextromethorphan and its metabolite 3-hydroxymorphinan. Neurochem Int. 2009 Jul;54(8):526-34.
Ref 533095Suppression of calcium current in a snail neurone by eperisone and its analogues. Eur J Pharmacol. 1989 Sep 22;168(3):299-305.

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