Drug General Information
Drug ID
D0P6YO
Former ID
DIB009953
Drug Name
NSD-721
Synonyms
NS-11394; NS-2552; NS-2664; GABA-A receptor modulators, NeuroSearch; GABA-A receptor modulators, NeuroSearch/Meiji Seika
Indication Anxiety disorder [ICD9: 300, 311; ICD10:F32, F40-F42] Terminated [546776]
Company
NeuroSearch A/S
Structure
Download
2D MOL

3D MOL

Canonical SMILES
CC(C)(c1cc2ncn(c3cc(ccc3)c3c(cccc3)C#N)c2cc1)O
CAS Number
CAS 468060-99-3
Target and Pathway
Target(s) GABA A receptor Target Info Modulator [543814]
KEGG Pathway Neuroactive ligand-receptor interaction
Retrograde endocannabinoid signaling
GABAergic synapse
Morphine addiction
Nicotine addiction
Reactome Ligand-gated ion channel transport
GABA A receptor activation
WikiPathways SIDS Susceptibility Pathways
Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell
Iron uptake and transport
References
Ref 546776Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800010233)
Ref 543814(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 415).

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