Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D0P6VV
|
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| Former ID |
DAP001100
|
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| Drug Name |
Dezocine
|
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| Drug Type |
Small molecular drug
|
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| Indication | Pain [ICD9: 338, 356.0, 356.8,780; ICD10:G64, G90.0, R52, G89] | Approved | [1] | ||
| Therapeutic Class |
Analgesics
|
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| Structure |
|
Download2D MOL |
|||
| Formula |
C16H23NO
|
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| Canonical SMILES |
CC12CCCCCC(C1N)CC3=C2C=C(C=C3)O
|
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| InChIKey |
VTMVHDZWSFQSQP-APHBMKBZSA-N
|
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| CAS Number |
CAS 53648-55-8
|
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| PubChem Compound ID | |||||
| PubChem Substance ID | |||||
| SuperDrug ATC ID |
N02AX03
|
||||
| SuperDrug CAS ID |
cas=053648558
|
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| Target and Pathway | |||||
| Target(s) | Kappa-type opioid receptor | Target Info | Antagonist | [2] | |
| KEGG Pathway | Neuroactive ligand-receptor interaction | ||||
| PANTHER Pathway | Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway | ||||
| Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway | |||||
| Opioid prodynorphin pathway | |||||
| Reactome | Peptide ligand-binding receptors | ||||
| G alpha (i) signalling events | |||||
| WikiPathways | GPCRs, Class A Rhodopsin-like | ||||
| Peptide GPCRs | |||||
| GPCR ligand binding | |||||
| GPCR downstream signaling | |||||
| References | |||||
| REF 1 | Natural products as sources of new drugs over the last 25 years. J Nat Prod. 2007 Mar;70(3):461-77. Epub 2007 Feb 20. | ||||
| REF 2 | Pharmacological profiles of opioid ligands at kappa opioid receptors. BMC Pharmacol. 2006 Jan 25;6:3. | ||||
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