Drug Information
Drug General Information | |||||
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Drug ID |
D0P5AE
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Former ID |
DIB014086
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Drug Name |
Ecallantide
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Synonyms |
FOV-2302; Retinal venous occlusion therapy, Fovea; Ecallantide (ophthalmic formulation/retinal disease); Ecallantide (ophthalmic formulation/retinal disease), Dyax/Fovea; DX-88 (ophthalmic formulation/retinal disease), Dyax/Fovea
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Drug Type |
Small molecular drug
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Company |
Dyax Corp
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Structure |
Download2D MOL |
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Formula |
C305H442N88O91S8
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PubChem Compound ID | |||||
PubChem Substance ID | |||||
Target and Pathway | |||||
Target(s) | Kallikrein | Target Info | Inhibitor | [536771] | |
Plasma kallikrein | Target Info | Inhibitor | [536771] | ||
KEGG Pathway | Complement and coagulation cascades | ||||
NetPath Pathway | AndrogenReceptor Signaling Pathway | ||||
PANTHER Pathway | Blood coagulation | ||||
PathWhiz Pathway | Coagulation | ||||
References | |||||
Ref 522774 | ClinicalTrials.gov (NCT00969293) Study to Assess the Safety and Tolerability of a Single Administration of FOV2302 (Ecallantide) in Patients With Macular Edema Associated With Central Retinal Vein Occlusion. U.S. National Institutes of Health. | ||||
Ref 541991 | (http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 6955). |
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