Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D0P2IN
|
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| Former ID |
DNC007832
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| Drug Name |
5'-amino-5'-deoxy-alpha-D-thymidine
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent | Investigative | [1] | ||
| Structure |
|
Download2D MOL |
|||
| Formula |
C10H15N3O4
|
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| Canonical SMILES |
CC1=CN(C(=O)NC1=O)C2CC(C(O2)CN)O
|
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| InChI |
1S/C10H15N3O4/c1-5-4-13(10(16)12-9(5)15)8-2-6(14)7(3-11)17-8/h4,6-8,14H,2-3,11H2,1H3,(H,12,15,16)/t6-,7+,8-/m0/s1
|
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| InChIKey |
PYWLBQPICCQJFF-RNJXMRFFSA-N
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| PubChem Compound ID | |||||
| Target and Pathway | |||||
| Target(s) | Thymidine monophosphate kinase | Target Info | Inhibitor | [1] | |
| KEGG Pathway | Pyrimidine metabolism | ||||
| Metabolic pathways | |||||
| References | |||||
| REF 1 | J Med Chem. 2007 Nov 1;50(22):5281-92. Epub 2007 Oct 2.Rational design of 5'-thiourea-substituted alpha-thymidine analogues as thymidine monophosphate kinase inhibitors capable of inhibiting mycobacterial growth. | ||||
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