Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D0P2CK
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| Former ID |
DAP000930
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| Drug Name |
Estazolam
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| Synonyms |
Cannoc; Esilgan; Estazolamum; Eurodin; Julodin; Nemurel; Nuctalon; ProSom; Somnatrol; Tasedan; Abbott Brand of Estazolam; HormonaBrand of Estazolam; Takeda Brand of Estazolam; Abbott 47631; D 40TA; D40TA; U 33737; D-40TA; Estazolamum [INN-Latin]; Eurodin (TN); ProSom (TN); Prosom (TN); Estazolam [USAN:INN:JAN]; Estazolam (JP15/USAN/INN); 4H-(1,2,4)Triazolo(4,3-a)(1,4)benzodiazepine, 8-chloro-6-phenyl; 8-Chloro-6-phenyl-4H-(1,2,4)triazolo-(4,3-a)(1,4)benzodiazepine; 8-Chloro-6-phenyl-4H-[1,2,4]triazolo[4,3-a][1,4]benzodiazepine; 8-Chloro-6-phenyl-4H-s-triazolo(4,3-a)(1,4)benzodiazepine; 8-Chloro-6-phenyl-4H-s-triazolo(4,3-a)(1,4)benzodiazepine (IUPAC); 8-Chloro-6-phenyl-4H-s-triazolo[4,3-a][1,4]benzodiazepine; 8-chloro-6-phenyl-4H-s-triazolo[4,3-(alpha)] [1,4]benzodiazepine
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| Drug Type |
Small molecular drug
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| Therapeutic Class |
Anticonvulsants
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| Structure |
|
Download2D MOL |
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| Formula |
C16H11ClN4
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| InChI |
InChI=1S/C16H11ClN4/c17-12-6-7-14-13(8-12)16(11-4-2-1-3-5-11)18-9-15-20-19-10-21(14)15/h1-8,10H,9H2
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| InChIKey |
CDCHDCWJMGXXRH-UHFFFAOYSA-N
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| CAS Number |
CAS 29975-16-4
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| PubChem Compound ID | |||||
| PubChem Substance ID |
9195, 145301, 5199055, 7847377, 7979189, 8152069, 10517653, 11528596, 15419098, 24894524, 29222400, 46507430, 48413727, 48415955, 50113063, 50257507, 53788680, 57321687, 58106946, 81041129, 87688132, 93166639, 99313646, 103209579, 104302993, 109611576, 125347364, 126665806, 127607634, 131309454, 134338206, 134997768, 136949636, 137005120, 137440701, 137783733, 144206162, 160964548, 164814347, 164841049, 170507541, 175265512, 179116671, 198993228, 221672875, 223365886, 223667151, 224783997, 226416014, 241050443
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| SuperDrug ATC ID |
N05CD04
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| SuperDrug CAS ID |
cas=029975164
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| Target and Pathway | |||||
| Target(s) | Peripheral-type benzodiazepine receptor | Target Info | Agonist | [535677], [536079] | |
| KEGG Pathway | Neuroactive ligand-receptor interaction | ||||
| HTLV-I infection | |||||
| References | |||||
| Ref 538287 | FDA Approved Drug Products from FDA Official Website. 2009. Application Number: (ANDA) 074818. | ||||
| Ref 542551 | (http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 7550). | ||||
| Ref 535677 | Design and synthesis of 4H-3-(2-phenoxy)phenyl-1,2,4-triazole derivatives as benzodiazepine receptor agonists. Bioorg Med Chem. 2003 Mar 6;11(5):769-73. | ||||
| Ref 536079 | Design and synthesis of new 2-substituted-5-(2-benzylthiophenyl)-1,3,4-oxadiazoles as benzodiazepine receptor agonists. Bioorg Med Chem Lett. 2005 Jun 15;15(12):3126-9. | ||||
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