Drug General Information
Drug ID
D0OG5K
Former ID
DAP001228
Drug Name
Bismuth
Synonyms
Bismut; Bismuto; Wismut; Bismuth standard for AAS; Bismuth standard for ICP; LTBB002773; Bismuth(III) nitrate solution; Bismuth, elemental; Bismuth-209; BISMUTH, 99.95%; BISMUTH, 99.999%; 83Bi
Drug Type
Small molecular drug
Indication Diarrhea [ICD9: 787.91; ICD10:A09, K59.1] Approved [529749]
Therapeutic Class
Antidiarrheals
Structure
Download
2D MOL

3D MOL

Formula
C9H64Bi10O25
Canonical SMILES
C(O)O.C(O)O.C(O)O.C(O)O.C(O)O.C(O)O.C(O)O.C(O)O.C(O)O.O<br />.O.O.O.O.O.O.[BiH2].[BiH2].[BiH2].[BiH2].[BiH2].[BiH2].<br />[BiH2].[Bi].[Bi].[Bi]
InChI
1S/9CH4O2.10Bi.7H2O.14H/c9*2-1-3;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;/h9*2-3H,1H2;;;;;;;;;;;7*1H2;;;;;;;;;;;;;;
InChIKey
LMVFRCLYOXEESX-UHFFFAOYSA-N
CAS Number
CAS 7440-69-9
PubChem Compound ID
PubChem Substance ID
ChEBI ID
ChEBI:33301
Target and Pathway
Target(s) Serum albumin Target Info Binder [535086]
Pathway Interaction Database FOXA2 and FOXA3 transcription factor networks
Reactome Platelet degranulation
Recycling of bile acids and salts
HDL-mediated lipid transport
Scavenging of heme from plasma
WikiPathways Human Complement System
Binding and Uptake of Ligands by Scavenger Receptors
Lipid digestion, mobilization, and transport
Transport of vitamins, nucleosides, and related molecules
Bile acid and bile salt metabolism
Folate Metabolism
Vitamin B12 Metabolism
Selenium Micronutrient Network
References
Ref 529749The effect of histamine H2-receptor blockade on bismuth absorption from three ulcer-healing compounds. Gastroenterology. 1991 Oct;101(4):889-94.
Ref 535086Competitive binding of bismuth to transferrin and albumin in aqueous solution and in blood plasma. J Biol Chem. 2001 Mar 23;276(12):8829-35. Epub 2000 Dec 7.

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